3-Fluorophenylboronic acid → HCID 86595314, compound

HRID 447193Notes

Reaction equation

HRID 447193 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.[F:16][C:17]1[CH:18]=[C:19](B(O)O)[CH:20]=[CH:21][CH:22]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([C:21]3[CH:20]=[CH:19][CH:18]=[C:17]([F:16])[CH:22]=3)[CH:14]=2)[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 27339863-Fluorophenylboronic acidHCID 178418879HCID 178418879, compound

Product 1

HCID 86595314HCID 86595314, compound

Procedure

The title compound, MS: m/e=312.5 (M+H+), was prepared in accordance with the general method of example 7 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 3-fluorobenzene boronic acid.

Sources & evidence

ORD record
ord-3636cc72bc8945c0aac89e67d7d1909d
Source dataset
uspto-grants-2013_07
Patent number
US08481548B2

Reaction notes

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