HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-(trifluoromethyl)pyrimidine → 4-[4-(2-Chloro-pyridin-4-ylethynyl)-2-methyl-imidazol-1-yl]-2-trifluoromethyl-pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-(trifluoromethyl)pyrimidine | HCID 15294369 | — |
| Reactant | HCID 178418879 | HCID 178418879 | — |
| Product | 4-[4-(2-Chloro-pyridin-4-ylethynyl)-2-methyl-imidazol-1-yl]-2-trifluoromethyl-pyrimidine | HCID 11740009 | — |
Reaction Steps
The title compound, MS: m/e=364.5 (M+H+), was prepared in accordance with the general method of example 3 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 4-chloro-2-trifluoromethyl-pyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481548B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-d7d97150d1264cfbb770e64b58b2eb37 |
| Source note | uspto-grants-2013_07 |