HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 447702Generated: October 30, 2026
Phosphorus oxychloride → HCID 14000270, compound
https://huagongshe.com/reaction/447702
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 86618739 | HCID 86618739 | — |
| Product | HCID 14000270 | HCID 14000270 | 84.8% |
Reaction Steps
A suspension of N-(4-amino-6-chloropyrimidin-5-yl)-N-methylbenzamide (0.285 g, 0.00108 mol) in phosphoryl chloride (8 mL, 0.08 mol) was heated at 115° C. overnight. The mixture was cooled, concentrated and triturated in diethyl ether to obtain 224 mg (84.4%) yellow solid. LC/MS: Rt=1.30 min, ES+ 245.08 (AA standard).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08481550B2 |
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| Source dataset | uspto-grants-2013_07 |
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| ORD ID | ord-79aced8b9dee44e69177223a9437bbb6 |
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| Source note | uspto-grants-2013_07 |
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