HCID 86653094, compound → HCID 58248312, compound

HRID 447709Notes

Reaction equation

HRID 447709 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([NH:11][C:12]([S:14][CH3:15])=[S:13])=[C:6]([CH:10]=1)[C:7](O)=[O:8]>C(OC(=O)C)(=O)C>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:12]([S:14][CH3:15])[S:13][C:7](=[O:8])[C:6]=2[CH:10]=1

Participants

3

Reactant 1

HCID 86653094HCID 86653094, compound

Product 1

HCID 58248312HCID 58248312, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

Compound 3 (2.85 g, 11.8 mmol) was dissolved in 50 mL of acetic anhydride and heated at reflux for 1 hour. The mixture was cooled to room temperature and the precipitate was filtered off. The crude product was recrystallized from ethyl alcohol to give 5 as white needle-shaped crystals (2.17 g, 83%). mp: 113.6° C.

Workup

  1. temperatureheated
  2. temperatureat reflux for 1 hour
  3. filtrationthe precipitate was filtered off
  4. customThe crude product was recrystallized from ethyl alcohol

Sources & evidence

ORD record
ord-49bb4bd955a0448bbd79c398555c8031
Source dataset
uspto-grants-2013_07
Patent number
US08481561B2

Reaction notes

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