5-Propionyloxindole → 5-Benzoyl-1,3-dihydro-2H-indol-2-one

HRID 4478Notes

Reaction equation

HRID 4478 reaction equation
C(C1C=C2C(=CC=1)NC(=O)C2)(=O)C.C(C1C=C2C(=CC=1)NC(=O)C2)(=O)CC.C1(C(C2C=C3C(=CC=2)NC(=O)C3)=O)SC=CC=1.C1SC=CC=1C(C1C=C2C(=CC=1)NC(=O)C2)=O.CC1C(C(=O)C)=CC=C2C=1CC(=O)N2.ClC1C(C(=O)C)=CC=C2C=1CC(=O)N2.C[C:91]1[CH:92]=[C:93]([C:101](=[O:108])[C:102]2[CH:107]=[CH:106][CH:105]=[CH:104][CH:103]=2)[CH:94]=[C:95]2[C:99]=1[NH:98][C:97](=[O:100])[CH2:96]2>>[C:101]([C:93]1[CH:94]=[C:95]2[C:99](=[CH:91][CH:92]=1)[NH:98][C:97](=[O:100])[CH2:96]2)(=[O:108])[C:102]1[CH:103]=[CH:104][CH:105]=[CH:106][CH:107]=1

Participants

8

Reactant 7

HCID 101764615-PropionyloxindoleHCID 102196435-acetyl-2,3-dihydro-1H-indol-2-oneHCID 135656705-(2-Thenoyl)oxindoleHCID 212820534-Methyl-5-acetyloxindoleHCID 212820817-Methyl-5-benzoyloxindoleHCID 212821054-Chloro-5-acetyloxindoleHCID 434629595-(3-Thenoyl)oxindole

Product 1

HCID 134081645-Benzoyl-1,3-dihydro-2H-indol-2-one

Procedure

Using a similar procedure and starting with the requisite reagents, 5-acetyloxindole, 5-propionyloxindole, 5-(2-thenoyl)oxindole, 5-(3-thenoyl)oxindole, 4-methyl-5-acetyloxindole, 4-chloro-5-acetyloxindole and 7-methyl-5-benzoyloxindole are prepared.

Workup

  1. customare prepared

Sources & evidence

ORD record
ord-6162f81a014e484d9b8d5eb5cdb0fc03
Source dataset
uspto-grants-1988_02
Patent number
US04725616

Reaction notes

Loading…