Methylamine → HCID 24952148, compound

Participants

Reaction Steps

To a solution of Example 45 in methanol was added a solution of methylamine in methanol and stirred overnight. The title compound was obtained by concentration of the reaction solution. 1H NMR (300 MHz, DMSO-D6) δ ppm 0.92 (t, J=7.29 Hz, 3 H) 1.23-1.37 (m, 2 H) 1.71 (m, 2 H) 2.74 (d, J=4.75 Hz, 4 H) 3.87 (s, 3 H) 4.15-4.24 (m, 2 H) 6.66 (s, 1 H) 7.14 (d, J=8.81 Hz, 1 H) 7.21 (s, 1 H) 7.44 (dd, J=8.82, 2.71 Hz, 1 H) 7.66 (d, J=2.71 Hz, 1 H) 8.77 (d, J=4.75 Hz, 1 H). MS (DCI) m/z 381 (M+H)+. Anal calcd for C18H21ClN2O3S.1.2H2O.0.3 NH4OH: C, 52.81; H, 6.03; N, 7.87. Found: C, 52.52; H, 5.70; N, 7.81.

Provenance & Evidence