HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66632589, compound → 4-methylnaphthalen-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66632589 | HCID 66632589 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-methylnaphthalen-1-amine | HCID 431187 | 96.9% |
Reaction Steps
To a solution of 1-methyl-4-nitro-naphthyl-amine (4.0 g, 21 mmol) in ethanol (300 mL) was added Raney-Nickel (4 scoops). The mixture was stirred under H2 (1 atm) for 16 h. The reaction was filtered through a pad of Celite and concentrated. Purification by silica gel flash column chromatography (EtOAc:Hexanes=15:85) provided product (3.2 g, 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481581B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-7e4a29393c1e41698fdcc0d878680b42 |
| Source note | uspto-grants-2013_07 |