HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(1H-Imidazol-2-yl)-pyridine → (R)-8-cyclopropyl-7-ethyl-5-methyl-2-(2-(pyridin-4-yl)-1H-imidazol-1-yl)-7,8-dihydropteridin-6(5H)-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(1H-Imidazol-2-yl)-pyridine | HCID 316817 | — |
| Edukt | (R)-2-chloro-8-cyclopropyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one | HCID 58405375 | — |
| Produkt | (R)-8-cyclopropyl-7-ethyl-5-methyl-2-(2-(pyridin-4-yl)-1H-imidazol-1-yl)-7,8-dihydropteridin-6(5H)-one | HCID 58405779 | — |
Reaktionsschritte
The title compound was prepared similarly to the methods described in Example 77, with Intermediate O instead of Intermediate C and with 4-(1H-imidazol-2-yl)pyridine instead of 2-phenyl-1H-imidazole. LCMS: 376.1 m/z (M+H)+; ret. Time: 3.90 min (Analytical Method C).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08541418B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-138f1e0e2443425985b5fa47c1c6cf2c |
| Quellennotiz | uspto-grants-2013_09 |