HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2,4-dichloro-N-(1-methyltetrazol-5-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2,4-Dichlorobenzoyl chloride | HCID 66645 | — |
| Reactant | 1-methyl-1H-tetrazol-5-amine | HCID 138492 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 2,4-dichloro-N-(1-methyltetrazol-5-yl)benzamide | HCID 66606525 | — |
Reaction Steps
In a microwave oven, 209 mg (1.0 mmol) of 2,4-dichlorobenzoyl chloride, 198 mg (2.0 mmol) of 1-methyl-5-aminotetrazole and 237 mg (3 mmol) of pyridine in 3 ml of acetonitrile are stirred at 130° C. for 45 min. Water is then added, and the product is filtered off with suction and washed with ether. Yield 80 mg (30%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481749B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-1e077ed3306f4005a44ab0d8c8cd395b |
| Source note | uspto-grants-2013_07 |