HRID448928

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)OC(=O)CCCOc1cc(Cl)c(Br)cc1C(=O)OCC[Si](C)(C)C

HCID68602708

未命名化合物

结构：CC1(C)OB(c2ccccc2C(=O)OCC[Si](C)(C)C)OC1(C)C

HCID86642577

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)CCCOc1cc(Cl)c(B2OC(C)(C)C(C)(C)O2)cc1C(=O)OCC[Si](C)(C)C

HCID68604491

未命名化合物

PROCEDURE

实验过程

2-(3-tert-Butoxycarbonyl-propoxy)-4-chloro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl-benzoic acid-2-trimethylsilanyl-ethyl ester (2.7 g) was similarly prepared according to Step 2D from 5-bromo-2-(3-tert-butoxycarbonyl-propoxy)-4-chloro-benzoic acid 2-trimethylsilanyl-ethyl ester (3.2 g). MS ion (APCl): 513.2, 459.1; tR=3.62 min. (method 1)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4c7a18e242c14bb9be9579e7443ce1c4
来源数据集: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08481738B2
来源说明: uspto-grants-2013_07

反应 SMILES

C[Si](C)(C)CCOC(=O)C1C=CC=CC=1[B:13]1[O:17][C:16]([CH3:19])([CH3:18])[C:15]([CH3:21])([CH3:20])[O:14]1.[CH3:25][Si:26]([CH3:52])([CH3:51])[CH2:27][CH2:28][O:29][C:30](=[O:50])[C:31]1[CH:36]=[C:35](Br)[C:34]([Cl:38])=[CH:33][C:32]=1[O:39][CH2:40][CH2:41][CH2:42][C:43]([O:45][C:46]([CH3:49])([CH3:48])[CH3:47])=[O:44]>>[CH3:25][Si:26]([CH3:52])([CH3:51])[CH2:27][CH2:28][O:29][C:30](=[O:50])[C:31]1[CH:36]=[C:35]([B:13]2[O:17][C:16]([CH3:19])([CH3:18])[C:15]([CH3:21])([CH3:20])[O:14]2)[C:34]([Cl:38])=[CH:33][C:32]=1[O:39][CH2:40][CH2:41][CH2:42][C:43]([O:45][C:46]([CH3:49])([CH3:48])[CH3:47])=[O:44]