HCID 66915518, compound → HCID 66915835, compound

HRID 449042Notes

Reaction equation

HRID 449042 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]([CH:18]3[CH2:21][CH2:20][CH2:19]3)[N:11]3[CH:16]=[CH:15][N:14]=[C:13]([NH2:17])[C:12]=23)=[CH:4][CH:3]=1.BrC1C=CC(B2OC(C)(C)[C:31](C)(C)[O:30]2)=CC=1OC>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:9]=[C:10]([CH:18]3[CH2:21][CH2:20][CH2:19]3)[N:11]3[CH:16]=[CH:15][N:14]=[C:13]([NH2:17])[C:12]=23)=[CH:6][C:7]=1[O:30][CH3:31]

Participants

3

Reactant 2

HCID 66915518HCID 66915518, compoundHCID 66915525HCID 66915525, compound

Product 1

HCID 66915835HCID 66915835, compound

Procedure

Prepared according to a procedure analogous to that described for 1-(4-bromophenyl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-ylamine except using 2-(4-bromo-3-methoxy-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane. MS (ES+): m/z 372.99, 374.96 [MH+].

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-841794e5dadd43918018b1c48c69f20a
Source dataset
uspto-grants-2013_07
Patent number
US08481733B2

Reaction notes

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