Thiophenol → HCID 57960824, compound

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Reaction Steps

Prepared according to a procedure analogous to that described for 3-cyclobutyl-1-[4-(2-fluoro-phenoxy)-3-methoxy-phenyl]-imidazo[1,5-a]pyrazin-8-ylamine except using benzenethiol. 1H NMR (400 MHz, CDCl3)-6=1.99-2.11 (m, 1H), 2.13-2.26 (m, 1H), 2.45-2.55 (m, 2H), 2.57-2.69 (m, 2H), 3.75-3.85 (m, 1H), 3.97 (s, 3H), 5.44 (br. s., 2H), 6.82 (d, J=5.6 Hz, 1H), 7.00-7.08 (m, 3H), 7.17 (d, J=1.3 Hz, 1H), 7.34-7.43 (m, 3H), 7.45-7.51 (m, 2H). MS (ES+): m/z 402.96 (100) [MH+].

Provenance & Evidence