HCID 44539191, compound → HCID 57960886, compound

HRID 449076Notes

Reaction equation

HRID 449076 reaction equation
NC1C=C(C=CC=1)OC1C=CC(C2N=C(C3CCC3)N3C=CN=C(N)C=23)=CC=1.[CH:29]1([C:33]2[N:37]3[CH:38]=[CH:39][N:40]=[C:41]([NH2:42])[C:36]3=[C:35]([C:43]3[CH:48]=[CH:47][C:46]([O:49][C:50]4[CH:55]=[CH:54][CH:53]=[CH:52][CH:51]=4)=[C:45]([N+:56]([O-])=O)[CH:44]=3)[N:34]=2)[CH2:32][CH2:31][CH2:30]1>>[NH2:56][C:45]1[CH:44]=[C:43]([C:35]2[N:34]=[C:33]([CH:29]3[CH2:32][CH2:31][CH2:30]3)[N:37]3[CH:38]=[CH:39][N:40]=[C:41]([NH2:42])[C:36]=23)[CH:48]=[CH:47][C:46]=1[O:49][C:50]1[CH:51]=[CH:52][CH:53]=[CH:54][CH:55]=1

Participants

3

Reactant 2

HCID 44539191HCID 44539191, compoundHCID 57960940HCID 57960940, compound

Product 1

HCID 57960886HCID 57960886, compound

Procedure

Prepared according to a procedure analogous to that described for 1-[4-(3-aminophenoxy)-phenyl]-3-cyclobutylimidazo[1,5-a]pyrazin-8-ylamine, except using 3-cyclobutyl-1-(3-nitro-4-phenoxy-phenyl)-imidazo[1,5-a]pyrazin-8-ylamine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-61aa6825beda464b84a3154201fdec19
Source dataset
uspto-grants-2013_07
Patent number
US08481733B2

Reaction notes

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