Boron tribromide → 2-Phenoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

Participants

Reaction Steps

To a solution of 2-(3-methoxy-4-phenoxyphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (50 mg, 0.0002 mol) in DCM (3 mL) was slowly added boron tribromide (0.145 mL, 0.00153 mol) at −20° C. The reaction was stirred at that temperature for 2 h. The reaction mixture was concentrated in vacuo and dried on the pump. The crude reaction mixture was used for next step without further purification.

Provenance & Evidence