4-Bromobenzophenone → HCID 15328860, compound

Participants

Reaction Steps

To a stirred solution of ethylmagnesium chloride (153.1 mg, 1.723 mmol) in THF (10.0 mL, 123 mmol) was added zinc dichloride (47.0 mg, 0.345 mmol) at rt. The resulting mixture was stirred at rt for 1 h. Then to this mixture, (4-bromophenyl)phenyl methanone (300.00 mg, 1.1489 mmol) in THF (5 mL) was added at 0° C. The mixture was then stirred at 0° C. for 2 h. The solvent was then removed under reduced pressure and the resulting residue was purified by a flash chromatography(2% EtOAc in hexane).

Provenance & Evidence