関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | Methyl quinoline-6-carboxylate | HCID 736812 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Quinoline-6-carboxamide | HCID 11052097 | 88% |
反応手順
To a solution of methyl quinoline-6-carboxylate (148 g, 0.79 mol) in methanol (600 ml.), aqueous ammonia (800 ml) was added and then stirred at 45° C. for 12 h. The reaction mixture was concentrated to afford the title compound as a dark red solid (120 g, 88%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08481739B2 |
|---|
| 出典データセット | uspto-grants-2013_07 |
|---|
| ORD ID | ord-2064bc2c1664413890efaae10aeac9f7 |
|---|
| 出典メモ | uspto-grants-2013_07 |
|---|
