HRID449352

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6371

Phosgene

CCl2O

HCID1201417

2-Thiazolamine, 4-(trifluoromethyl)-

C4H3F3N2S

结构：CN1CCN(c2cc(-c3ccc4c(c3)CNCC4)nc(N)n2)CC1.Cl

HCID67541489

未命名化合物

PRODUCTS

生成物

结构：CN1CCN(c2cc(-c3ccc4c(c3)CN(C(=O)Nc3nc(C(F)(F)F)cs3)CC4)nc(N)n2)CC1

HCID59496590

未命名化合物

PROCEDURE

实验过程

This compound was prepared by using procedures analogous to those described for the synthesis of Example 40 starting from 4-(trifluoromethyl)-1,3-thiazol-2-amine (Oakwood, Cat. #009875), phosgene and 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt. Analytic LCMS (M+H)+: m/z=519.2.

WORKUP

后处理

customThis compound was prepared