HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 67541770, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate | HCID 151348 | — |
| Reactant | HCID 59496679 | HCID 59496679 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 67541770 | HCID 67541770 | — |
Reaction Steps
This compound was prepared by using procedures analogous to those described for the synthesis of Example 41 starting from dimethylamine (2.0 M solution in THF), (S)-2-(7-(2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl)-1,2,3,4-tetrahydroisoquinoline-2-carboxamido)-3-phenylpropanoic acid, triethylamine, and benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate. Analytic LCMS (M+H)+: m/z=543.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481732B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-76c89ae02be84d5883e0fe74bf2b7622 |
| Source note | uspto-grants-2013_07 |