Hydrochloric Acid → HCID 67541963, compound

Participants

Reaction Steps

tert-Butyl [1-{[6-(2,3-difluorophenyl)pyridin-3-yl]methyl}-2-(dimethylamino)-2-oxoethyl]carbamate (60 mg, 0.10 mmol) was dissolved in 4 M of hydrogen chloride in 1,4-dioxane (2 mL, 8 mmol) at r.t. The reaction was stirred for 1 h., and concentrated under reduced pressure to give crude 2-amino-3-[6-(2,3-difluorophenyl)pyridin-3yl]-N,N-dimethylpropanamide HCl salt (0.040 g, 50%) as colorless oil. Analytical LCMS (M+H)+: m/z=306.0.

Provenance & Evidence