3-(4-Methoxyphenoxy)benzaldehyde oxime → HCID 3325091, compound

HRID 449513Notes

Reaction equation

HRID 449513 reaction equation
[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([O:7][C:8]2[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=2)[CH:11]=[N:12]O)=[CH:5][CH:4]=1>C(O)(=O)C.[Zn]>[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([O:7][C:8]2[CH:9]=[C:10]([CH2:11][NH2:12])[CH:14]=[CH:15][CH:16]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 1

HCID 723078873-(4-Methoxyphenoxy)benzaldehyde oxime

Product 1

HCID 3325091HCID 3325091, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 176Acetic AcidSolvent

Procedure

The 3-(4-methoxyphenoxy)benzaldehyde oxime (0.11 g, 0.44 mmol) was taken up in acetic acid (5.0 mL) at rt and the Zinc dust (0.14 g, 2.2 mmol) was added. The reaction was stirred at r.t. for 18 h. The reaction mixture was filtered and the filtrate was concentrated under reduced pressure to give crude 1-[3-(4-methoxyphenoxy)phenyl]methanamine as a dark oil. Analytical LCMS (M+H)+: m/z=, 229.9

Workup

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-27e84c676f0c40da81f2a72c5c5c06a4
Source dataset
uspto-grants-2013_07
Patent number
US08481732B2

Reaction notes

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