HCID 66752394, compound → HCID 91870398, compound

HRID 449545Notes

Reaction equation

FC1C=C(OC)C=C(F)C=1[C:11]1=[C:12]([CH:42]=[CH:43][C:44]2[C:52]([CH3:54])([CH3:53])[C:51]3[C:46](=[CH:47][CH:48]=[C:49]([S:55]([O-:58])(=[O:57])=[O:56])[CH:50]=3)[N+:45]=2[CH2:59][CH2:60][CH2:61][CH2:62][S:63]([O-:66])(=[O:65])=[O:64])[CH2:13][CH2:14][CH2:15]/[C:16]/1=[CH:17]\[CH:18]=[C:19]1\[N:20]([CH2:34][CH2:35][CH2:36][CH2:37][S:38]([O-:41])(=[O:40])=[O:39])[C:21]2[C:26]([C:27]\1([CH3:29])[CH3:28])=[CH:25][C:24]([S:30]([O-:33])(=[O:32])=[O:31])=[CH:23][CH:22]=2.[Na+:67].[Na+].[Na+].B([C:73]1[C:74]([F:87])=[C:75]([CH:83]=[CH:84][C:85]=1[F:86])[O:76][CH2:77][CH2:78][CH2:79][C:80]([OH:82])=[O:81])(O)O>>[C:80]([CH2:79][CH2:78][CH2:77][O:76][C:75]1[C:74]([F:87])=[C:73]([C:11]2=[C:16]([CH:17]=[CH:18][C:19]3[C:27]([CH3:29])([CH3:28])[C:26]4[C:21](=[CH:22][CH:23]=[C:24]([S:30]([O-:33])(=[O:31])=[O:32])[CH:25]=4)[N+:20]=3[CH2:34][CH2:35][CH2:36][CH2:37][S:38]([O-:41])(=[O:40])=[O:39])[CH2:15][CH2:14][CH2:13]/[C:12]/2=[CH:42]\[CH:43]=[C:44]2\[N:45]([CH2:59][CH2:60][CH2:61][CH2:62][S:63]([O-:66])(=[O:65])=[O:64])[C:46]3[C:51]([C:52]\2([CH3:54])[CH3:53])=[CH:50][C:49]([S:55]([O-:58])(=[O:56])=[O:57])=[CH:48][CH:47]=3)[C:85]([F:86])=[CH:84][CH:83]=1)([OH:82])=[O:81].[Na+:67].[Na+:67].[Na+:67]

Participants

Reactant 2

HCID 66752394HCID 66752394, compound

HCID 86649231HCID 86649231, compound

Product 1

HCID 91870398HCID 91870398, compound

Procedure

Compound 37 is prepared analogously to compound 17, except with 4-(3-borono-2,4-difluorophenoxy)butanoic acid as a starting material.

Sources & evidence

ORD record: ord-6ba3f59861aa42b7ba694a2a4681859c
Source dataset: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08481752B2

Reaction notes

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