化工社化工社 化学情報印刷レポート · 研究参考用
1-(2-Dimethylaminoethoxy)-3-nitrobenzene → 3-[2-(Dimethylamino)ethoxy]aniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(2-Dimethylaminoethoxy)-3-nitrobenzene | HCID 21833117 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 3-[2-(Dimethylamino)ethoxy]aniline | HCID 16778205 | 85.1% |
反応手順
A solution of dimethyl-[2-(3-nitro-phenoxy)-ethyl]-amine (500 mg, 2.38 mmol) in methanol (20 ml) was hydrogenated over 10% Pd—C at 30 psi until no further gas uptake was observed. The reaction mixture was then filtered over celite and concentrated to yield 3-(2-dimethylamino-ethoxy)-phenylamine (365 mg, 85%) as viscous oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08486962B2 |
| 出典データセット | uspto-grants-2013_07 |
| ORD ID | ord-41022280e2e74564b4abfb95f2a2d4d7 |
| 出典メモ | uspto-grants-2013_07 |