HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 2,4-Dichloro-5-fluoro-3-nitrobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Benzoyl chloride, 2,4-dichloro-5-fluoro-3-nitro- | HCID 11818130 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2,4-Dichloro-5-fluoro-3-nitrobenzamide | HCID 86674494 | — |
Reaction Steps
32%-aq. NH3-solution (250 mL) is dropped to 2,4-dichloro-5-fluoro-3 nitro-benzoic acid chloride (16.0 g, 59 mmol) in 100 mL THF and it is stirred for 20 min. Then the mixture is concentrated and the resulting precipitate is collected and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486968B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-df08f57c65574d2dac6a5cf4ec7a4982 |
| Source note | uspto-grants-2013_07 |