HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylcarbodiimide → HCID 178453092, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylcarbodiimide | HCID 12734 | — |
| Reactant | HCID 86674498 | HCID 86674498 | — |
| Reactant | HCID 178507777 | HCID 178507777 | — |
| Product | HCID 178453092 | HCID 178453092 | — |
Reaction Steps
The subtitle compound is prepared in analogy to 2d from N-(trans-4-trifluoromethyl-cyclohexyl)-5,6-diamino-2-(4-fluoro-piperidinyl)-nicotinic acid amide, (2,4-dichloro-5-fluoro-3-isothiocyanato-benzyl)-carbamic acid tert-butyl ester and DIC. The product is purified via prep. HPLC (C-18 stable bond, eluent gradient: water(+0.15% HCOOH)/MeOH 9:1->MeOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486968B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-9448316570e24cb8b7449842d88ba2c4 |
| Source note | uspto-grants-2013_07 |