HCID 67398160, compound → HCID 86641684, compound

Participants

Reaction Steps

A solution of [4-(6-hydroxymethyl-pyridin-3-yloxy)-phenyl]-carbamic acid t-butyl ester (0.25 g, 0.8 mmol) in DCM (3.0 ml) was treated with activated MnO2 (0.42 g, 4.8 mmol) and the suspension was stirred at RT for 2 h. The reaction suspension was filtered and the filtrate was concentrated in vacuo to provide [4-(6-formyl-pyridin-3-yloxy)-phenyl]-carbamic acid t-butyl ester (0.24 g, 95% yield). MS (ESI) m/z: 315.0 (M+H+).

Provenance & Evidence