Ammonia → HCID 67026099, compound

HRID 450607Notes

Reaction equation

HRID 450607 reaction equation
[OH:1][N:2]=[C:3]([NH2:10])[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1.[CH3:11][C:12]1[N:13]=[CH:14][C:15]([C:18](O)=O)=[N:16][CH:17]=1.N>>[CH3:11][C:12]1[N:13]=[CH:14][C:15]([C:18]2[O:1][N:2]=[C:3]([C:4]3[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=3)[N:10]=2)=[N:16][CH:17]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 1228315-Methyl-2-pyrazinecarboxylic acidHCID 308113N-Hydroxynicotinimidamide

Product 1

HCID 67026099HCID 67026099, compound

Procedure

The title compound was prepared according to the procedure of Example 8 using N′-hydroxynicotinimidamide (Aldrich) and 5-methylpyrazine-2-carboxylic acid (Aldrich). 1H NMR (300 MHz, CD3OD) δ 2.71 (s, 3 H), 7.66 (ddd, J=8.0, 5.1, 0.8 Hz, 1 H), 8.59 (dt, J=7.9, 1.8 Hz, 1 H), 8.74-8.78 (m, 2 H), 9.33 (dd, J=2.0, 0.8 Hz, 1 H), 9.40 (d, J=1.2 Hz, 1 H) ppm; MS (DCI/NH3) m/z 240 (M+H)+.

Sources & evidence

ORD record
ord-2c0ee92b12914084a1b2ef37d9292d88
Source dataset
uspto-grants-2013_07
Patent number
US08486979B2

Reaction notes

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