Ammonia → HCID 44544770, compound

HRID 450669Notes

Reaction equation

HRID 450669 reaction equation
[OH:1][N:2]=[C:3]([C:5]1[CH:10]=[CH:9][N:8]=[N:7][CH:6]=1)[NH2:4].[F:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](Cl)=O)=[CH:14][CH:13]=1.N>>[F:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]2[O:1][N:2]=[C:3]([C:5]3[CH:10]=[CH:9][N:8]=[N:7][CH:6]=3)[N:4]=2)=[CH:14][CH:13]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 678794-Fluorobenzoyl chlorideHCID 136140373N-Hydroxy-4-pyridazinecarboximidamide

Product 1

HCID 44544770HCID 44544770, compound

Procedure

The titled compound was prepared according to the procedure of Method D using the product of Example 83D and 4-fluorobenzoyl chloride (Aldrich). 1H NMR (300 MHz, CD3OD) δ 7.36-7.45 (m, 2 H), 8.29-8.40 (m, 3 H), 9.45 (dd, J=5.6, 1.2 Hz, 1 H), 9.86 (dd, J=2.4, 1.2 Hz, 1 H) ppm; MS (DCI/NH3) m/z=243 (M+H)+.

Sources & evidence

ORD record
ord-49fa6ee105484da98d7f0a2a2fcf3353
Source dataset
uspto-grants-2013_07
Patent number
US08486979B2

Reaction notes

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