HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 44544871, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | N-Hydroxynicotinimidamide | HCID 308113 | — |
| Reactant | 2,2-Difluoro-1,3-benzodioxole-5-carboxylic acid | HCID 608772 | — |
| Product | HCID 44544871 | HCID 44544871 | — |
Reaction Steps
The title compound was prepared according to Method C using 2,2-difluorobenzo[d][1,3]dioxole-5-carboxylic acid (Aldrich) and N′-hydroxynicotinimidamide (Tyger). 1H NMR (300 MHz, DMSO-d6) δ 7.66 (ddd, J=8.1, 4.8, 1.0 Hz, 1 H), 7.73 (d, J=8.5 Hz, 1 H), 8.14 (dd, J=8.5, 1.7 Hz, 1 H), 8.25 (d, J=1.7 Hz, 1 H), 8.44 (dt, J=8.2, 1.9, 1.7 Hz, 1 H), 8.82 (dd, J=4.7, 1.7 Hz, 1 H), 9.25 (dd, J=2.2, 0.8 Hz, 1 H) ppm; MS (DCI/NH3) m/z 304 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486979B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-e0e436047c524a0594da78805c1d17aa |
| Source note | uspto-grants-2013_07 |