HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 3-(pyridin-3-yl)-5-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1,2,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | N-Hydroxynicotinimidamide | HCID 308113 | — |
| Reactant | 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid | HCID 21907018 | — |
| Product | 3-(pyridin-3-yl)-5-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1,2,4-oxadiazole | HCID 44544964 | — |
Reaction Steps
The title compound was prepared according to Method C using 1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid (Adesis) and N′-hydroxynicotinimidamide (Tyger). 1H NMR (300 MHz, DMSO-d6) δ 6.71 (d, J=3.4 Hz, 1 H), 7.66 (ddd, J=7.9, 4.8, 0.8 Hz, 1 H), 7.70 (d, J=3.4 Hz, 1 H), 8.47 (dt, J=8.1, 1.9 Hz, 1 H), 8.78-8.86 (m, 2 H), 9.05 (d, J=2.0 Hz, 1 H), 9.28 (dd, J=2.2, 0.8 Hz, 1 H) ppm; MS (DCI/NH3) m/z 264 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486979B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-294ce934fbd94da48c7a203bed97b709 |
| Source note | uspto-grants-2013_07 |