HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-(1-methyl-1H-benzo[d]imidazol-5-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | N-Hydroxynicotinimidamide | HCID 308113 | — |
| Reactant | 1-Methyl-1H-benzimidazole-5-carboxylic acid | HCID 4913063 | — |
| Product | 5-(1-methyl-1H-benzo[d]imidazol-5-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole | HCID 44544967 | — |
Reaction Steps
The title compound was prepared according to Method C using 1-methyl-1H-benzo[d]imidazole-5-carboxylic acid (Maybridge) and N′-hydroxynicotinimidamide (Tyger). 1H NMR (300 MHz, DMSO-d6) δ7.65 (ddd, J=8.0, 4.9, 0.7 Hz, 1 H), 7.68-7.88 (m, J=8.8 Hz, 1 H), 7.87-8.10 (m, 2 H), 8.14-8.37 (m, 1 H), 8.46 (dt, J=8.1, 1.9 Hz, 1 H), 8.82 (dd, J=4.7, 1.7 Hz, 1 H), 9.27 (dd, J=2.0, 0.7 Hz, 1 H) ppm; MS (DCI/NH3) m/z 278 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486979B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-fc80db57ecde49f08e09b225a0fd3856 |
| Source note | uspto-grants-2013_07 |