HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-(5-Fluoropyridin-3-yl)-3-(imidazo[1,2-a]pyridin-6-yl)-1,2,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 5-Fluoronicotinic Acid | HCID 120232 | — |
| Reactant | N'-hydroxyimidazo[1,2-a]pyridine-6-carboximidamide | HCID 2764575 | — |
| Product | 5-(5-Fluoropyridin-3-yl)-3-(imidazo[1,2-a]pyridin-6-yl)-1,2,4-oxadiazole | HCID 44545067 | — |
Reaction Steps
The title compound was prepared according to method C using N′-hydroxyimidazo[1,2-a]pyridine-6-carboximidamide (Bionet) and 5-fluoronicotinic acid (Frontier). 1H NMR (300 MHz, DMSO-d6) δ 7.71 (d, J=1.4 Hz, 1 H), 7.74-7.88 (m, 2 H), 8.20 (s, 1 H), 8.51 (ddd, J=9.0, 2.9, 1.7 Hz, 1 H), 8.97 (d, J=3.1 Hz, 1 H), 9.24 (t, J=1.5 Hz, 1 H), 9.47 (t, J=1.4 Hz, 1 H) ppm; MS (DCI/NH3) m/z 282 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486979B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-985854b8d1cc458090979eb405023a99 |
| Source note | uspto-grants-2013_07 |