(+)-2-Phenyl-1-propanol → toluene-4-sulfonic acid (R)-2-phenylpropyl ester

HRID 450709Notes

Reaction equation

HRID 450709 reaction equation
[C:1]1([C@H:7]([CH3:20])[CH2:8][O:9][S:10]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][CH:14]=2)(=[O:12])=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1([C@@H](C)CO)C=CC=CC=1>>[C:1]1([C@@H:7]([CH3:20])[CH2:8][O:9][S:10]([C:13]2[CH:14]=[CH:15][C:16]([CH3:19])=[CH:17][CH:18]=2)(=[O:12])=[O:11])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 177050(+)-2-Phenyl-1-propanolHCID 13791931Toluene-4-sulfonic acid (S)-2-phenyl-propyl ester

Product 1

HCID 13791929toluene-4-sulfonic acid (R)-2-phenylpropyl ester

Procedure

Following the procedure analogous to that used for the synthesis of toluene 4-sulfonic acid (S)-2-phenyl-propyl ester, but using (R)-2-phenyl-1-propanol, the title compound was prepared

Sources & evidence

ORD record
ord-ede18565ad2a46d2b9cdaef58a2b70e6
Source dataset
uspto-grants-2013_07
Patent number
US08486984B2

Reaction notes

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