HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 59478710, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 59478856 | HCID 59478856 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 59478710 | HCID 59478710 | 100% |
Reaction Steps
To a mixture of 1266 mg of {2-[(tetrahydro-2H-pyrane-2-yloxy)methyl]pyridin-4-yl}methyl benzoate and 25 ml of methanol was added 1166 mg of pyridinium p-toluenesulfonate, followed by stirring for 2 hours. A saturated aqueous sodium hydrogen carbonate solution and chloroform were added thereto for extraction, and the organic layer was dried over anhydrous magnesium sulfate and then concentrated under reduced pressure to obtain 941 mg of [2-(hydroxymethyl)pyridin-4-yl]methyl benzoate as an amorphous substance.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486970B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-e8dd940273aa4a89a9c649bc64b70f7e |
| Source note | uspto-grants-2013_07 |