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HRID451053

反应详情

EQUATION

反应方程式

HRID 451053 的结构方程式

REACTANTS

反应物

2
结构：COCC(N)C1CC1
HCID53414987

1-Cyclopropyl-2-methoxyethan-1-amine

C6H13NO

结构：Fc1ccc(C2CCc3c(Cl)nc(Cl)nc32)cc1
HCID58075424

未命名化合物

PRODUCTS

生成物

1
结构：COCC(Nc1nc(Cl)nc2c1CCC2c1ccc(F)cc1)C1CC1
HCID58075655

未命名化合物

PROCEDURE

实验过程

2,4-dichloro-7-(4-fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine (Preparation H) was reacted as described in Preparation Hr with 1-cyclopropyl-2-methoxyethanamine to afford 2-chloro-N-(1-cyclopropyl-2-methoxyethyl)-7-(4-fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine (Preparation Hw) as a mixture of 4 diasteriomers. LC-MS (M+H)+=362.1.