Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethynylcyclohexane → 1-Cyclohexylethynyl-3-trifluoromethyl-benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethynylcyclohexane | HCID 70263 | — |
| 반응물 | 1-(Tosyloxy)-3-(trifluoromethyl)benzene | HCID 11243986 | — |
| 용매 | Heptane | HCID 8900 | — |
| 생성물 | 1-Cyclohexylethynyl-3-trifluoromethyl-benzene | HCID 25221610 | — |
반응 단계
This product was prepared from toluene-4-sulfonic acid 3-trifluoromethyl-phenyl ester and ethynyl-cyclohexane following the general procedure for the Sonogashira cross-coupling process described above. Chromatography eluent: heptane; yield (82 mg, 65%); δH (CDCl3): 7.67 (s, 1H), 7.61-7.7.49 (m, 2H), 7.46-7.37 (m, 1H), 2.70-2.52 (m, 1H), 2.04-1.30 (m, 10H); LCMS m/z: 252.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08487109B2 |
| 출처 데이터셋 | uspto-grants-2013_07 |
| ORD ID | ord-81cf106f1bf84d18bd54591aa1a577e9 |
| 출처 메모 | uspto-grants-2013_07 |