HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dietylaminopropin → HCID 25221615, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dietylaminopropin | HCID 20010 | — |
| Reactant | Benzonitrile, 4-[[(4-methylphenyl)sulfonyl]oxy]- | HCID 11482693 | — |
| Solvent | Ethylacetate heptane | HCID 21899848 | — |
| Product | HCID 25221615 | HCID 25221615 | — |
Reaction Steps
This product was prepared from toluene-4-sulfonic acid 4-cyano-phenyl ester and diethyl-prop-2-ynyl-amine following the general procedure for the Sonogashira cross-coupling process described above. Chromatography eluent: heptane/EtOAc 6:4; yield (95.4 mg, 90%); 1H NMR δ (CDCl3): 7.58 (d, J=8.65 Hz, 2H), 7.49 (d, J=8.63 Hz, 2H), 3.64 (s, 2H), 2.61 (q, J=7.16 Hz, 4H), 1.11 (t, J=7.15 Hz, 6H); LCMS m/z: 212.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08487109B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-752d74782a8c41c5b3656ca0e45bbff2 |
| Source note | uspto-grants-2013_07 |