HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethynylaniline → 4-(4-Trifluoromethoxy-phenylethynyl)-phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethynylaniline | HCID 3760025 | — |
| Reactant | Toluene-4-sulfonic acid 4-trifluoromethoxy-phenyl ester | HCID 18424495 | — |
| Solvent | Heptane | HCID 8900 | — |
| Product | 4-(4-Trifluoromethoxy-phenylethynyl)-phenylamine | HCID 25221727 | — |
Reaction Steps
This product was prepared from toluene-4-sulfonic acid 4-trifluoromethoxy-phenyl ester and 4-ethynyl-phenylamine. Chromatography eluent: heptane; yield (111 mg, 80%); 1H NMR δ (CDCl3): 7.5 (d, J=8.42 Hz, 2H), 7.33 (d, J=8.60 Hz, 2H), 7.18 (d, J=8.41 Hz, 2H), 6.62 (d, J=8.62 Hz, 2H), 3.82 (s, 2H); LCMS m/z 277.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08487109B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-446b487ddeb148afb40c713e34567c8d |
| Source note | uspto-grants-2013_07 |