HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 451349Generated: October 29, 2026
Chloroacetic Acid → HCID 131730715, compound
https://huagongshe.com/reaction/451349
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chloroacetic Acid | HCID 300 | — |
| Reactant | Tizanidine | HCID 5487 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 131730715 | HCID 131730715 | — |
Reaction Steps
To a solution of 2.0 g of monochloroacetic acid in 10 ml of isopropyl alcohol 3.0 g of the tizanidine base (99.15% HPLC) are added. After brief heating to boil a solution results, from which a crystalline precipitated product starts to separate. After cooling to 0 to 5° C. and aspiration 3.31 g of tizanidine monochloroacetate are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08487113B2 |
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| Source dataset | uspto-grants-2013_07 |
|---|
| ORD ID | ord-9a34d4493c1146f19d46af4231fa21e6 |
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| Source note | uspto-grants-2013_07 |
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