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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 451388Generated: October 31, 2026

1-(3-chlorobenzyl)-1H-1,2,4-triazol-3-amine → [1-(3-Chloro-benzyl)-1H-[1,2,4]triazol-3-yl]-[1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-amine

https://huagongshe.com/reaction/451388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-chlorobenzyl)-1H-1,2,4-triazol-3-amineHCID 7019336—
Reactant1-(3-Methyl-1,2,4-thiadiazol-5-yl)piperidin-4-oneHCID 59258510—
Product[1-(3-Chloro-benzyl)-1H-[1,2,4]triazol-3-yl]-[1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-amineHCID 53354735—

Reaction Steps

Prepared in analogy to example 1 step h) starting from 1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-one (example 1c) and 1-(3-chloro-benzyl)-1H-[1,2,4]triazol-3-ylamine. The title compound was obtained as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08486967B2
Source datasetuspto-grants-2013_07
ORD IDord-b85f1fc14aa04f65b51636398a26d56e
Source noteuspto-grants-2013_07