HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-chlorobenzyl)-1H-pyrazol-3-amine → [1-(4-Chloro-benzyl)-1H-pyrazol-3-yl]-[1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-chlorobenzyl)-1H-pyrazol-3-amine | HCID 673690 | — |
| Reactant | 1-(3-Methyl-1,2,4-thiadiazol-5-yl)piperidin-4-one | HCID 59258510 | — |
| Product | [1-(4-Chloro-benzyl)-1H-pyrazol-3-yl]-[1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-amine | HCID 58397847 | — |
Reaction Steps
Prepared in analogy to example 1 step h) starting from 1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-one (example 1c) and 1-(4-chloro-benzyl)-1H-pyrazol-3-ylamine. The title compound was obtained as a white solid (yield=70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486967B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-416e665307a147e598f81057382ad22c |
| Source note | uspto-grants-2013_07 |