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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 451438Generated: October 31, 2026

2-Amino-6-Chloropyrazine → 6-(4-Fluorophenyl)-2-pyrazinamine

https://huagongshe.com/reaction/451438

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-6-ChloropyrazineHCID 118458—
Reactant4-Fluorophenylboronic acidHCID 285645—
Product6-(4-Fluorophenyl)-2-pyrazinamineHCID 45788339—

Reaction Steps

Prepared in analogy to example 1d, starting from 2-amino-6-chloropyrazine and 4-fluorobenzeneboronic acid. The title compound was obtained as a slightly brown solid (yield: 91%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08486967B2
Source datasetuspto-grants-2013_07
ORD IDord-cdf50d7a95e2483d9144d71230f35670
Source noteuspto-grants-2013_07