tert-Butyl carbazate → HCID 67336794, compound

Participants

Reaction Conditions

Reaction Steps

(2-Oxo-ethoxy)-phenyl-acetic acid methyl ester (2.7 g, 13.0 mmol) and tert-butyl carbazate (1.75 g, 13.0 mmol) were dissolved in toluene (290 mL) and heated to 65° C. over night. The reaction mixture was concentrated in vacuo and the residue was purified by flash chromatography (silica gel, 100 g, 0% to 100% EtOAc in heptane over 60 minutes) to give the title compound as yellow viscous oil (2.81 g, 67%).

Provenance & Evidence