HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131726886, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N'-(5-tert-Butyl-2,3-dihydro-1H-inden-1-yl)-N-1H-indazol-4-ylcarbamimidic acid | HCID 11256560 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 131726886 | HCID 131726886 | 41.3% |
Reaction Steps
Hydrochloric acid (37% aq, 17 mg) was added to a solution of compound of Example 13 (60 mg, 0.17 mmol) in THF 4 mL. After mixing for additional 15 h the precipitate was filtered off and dried to provide 27 mg (40%) of the salt. Differential scanning calorimetry and X-ray diffraction results are shown in FIGS. 3 and 4, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08487116B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-cb7075c7db1e40a292f27aab74fde208 |
| Source note | uspto-grants-2013_07 |