HCID 59201630, compound → HCID 59201315, compound

Participants

Reaction Steps

A solution of methyl 2-((R)-(3-chlorophenyl)((R)-1-((1S,2R)-1-cyclohexyl-1-hydroxy-3-(N-methyl-N-(tert-butoxycarbonyl)amino)propan-2-ylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate (5 mg, 0.008 mmol) in EtOH (2 mL) was stirred with 10% Pd/C (5 mg) under H2 overnight. The mixture was filtered thru Celite. After removal of solvent in vacuo, the residue was used directly in the next step.

Provenance & Evidence