反应详情

48 mg (91.7 μmol) of {1-[4-(Isoquinolin-6-ylamino)-1-(4-methoxy-phenyl)-cyclohexyl]-propyl}-carbamic acid benzyl ester (99) were dissolved in 300 μL of dry methanol and 9.7 μg of palladium on activated charcoal (10%) were added. The mixture was stirred under a hydrogen atmosphere until conversion was complete. The catalyst was filtered off and the reaction mixture was evaporated to dryness to give the title compound. Rt=0.89 min (Method 19). Detected mass: 390.3 (M+H+).

1. filtrationThe catalyst was filtered off
2. customthe reaction mixture was evaporated to dryness