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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 452066Generated: October 31, 2026

5-Aminobenzimidazole → HCID 178517611, compound

https://huagongshe.com/reaction/452066

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-AminobenzimidazoleHCID 13623—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 57488458HCID 57488458—
ProductHCID 178517611HCID 178517611—

Reaction Steps

The compound was synthesized as hydrochloride salt starting from 5-aminobenzimidazole (0.37 g, 2.78 mmol), di(1H-imidazol-1-yl)methanone (0.496 g, 3.06 mmol), TEA (1.16 mL, 8.34 mmol), aminomethyl-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ketone hydrobromide (0.761 g, 2.78 mmol), TEA (0.775 mL, 5.56 mmol), PdC (10%, 0.02 g) as described in method 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08486940B2
Source datasetuspto-grants-2013_07
ORD IDord-c622e35f29284cb89258059864c576e5
Source noteuspto-grants-2013_07