HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorobenzaldehyde → HCID 178517646, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorobenzaldehyde | HCID 11477 | — |
| Reactant | 5-Aminobenzimidazole | HCID 13623 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Trimethylsilyl cyanide | HCID 82115 | — |
| Reactant | Trifluoroacetate | HCID 84468 | — |
| Product | HCID 178517646 | HCID 178517646 | — |
Reaction Steps
The compound was synthesized as trifluoroacetate salt starting from 5-aminobenzimidazole (0.293 g, 2.2 mmol), 3-chloro benzaldehyde (0.227 mL, 2 mmol), TMSCN (0.25 mL, 2 mmol), PdC (10%, 0.01 g), TEA (0.613 mL, 4.4 mmol), di-(imidazol-1-yl)methanone (0.389 g, 2.4 mmol) as described in method 2. The product was purified by means of preparative HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486940B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-34046356ff984cfaa52eefa0b8e0fcf0 |
| Source note | uspto-grants-2013_07 |