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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 452106Generated: October 31, 2026

Veratraldehyde → HCID 178488768, compound

https://huagongshe.com/reaction/452106

Reaction equation

Participants

RoleNameHCIDCharge
ReactantVeratraldehydeHCID 8419—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantTrimethylsilyl cyanideHCID 82115—
ReactantHCID 178507353HCID 178507353—
CatalystPalladiumHCID 23938—
ProductHCID 178488768HCID 178488768—

Reaction Steps

The compound was synthesized starting from 1H-benzo[d]imidazol-5-amine (0.400 g, 3 mmol), 3,4-dimethoxybenzaldehyde (0.5 g, 3 mmol), TMSCN (0.375 mL, 3 mmol), Pd/C (10%, 0.02 g), TEA 1.05 mL, 7.5 mmol), di-(imidazol-1-yl)methanone (0.730 g, 4.5 mmol) as described in method 2 to give 1-(1H-benzo[d]imidazol-5-yl)-5-(3,4-dimethoxyphenyl)imidazolidin-2-one

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08486940B2
Source datasetuspto-grants-2013_07
ORD IDord-c9cc824081a2418eae0eff4fd78f77fe
Source noteuspto-grants-2013_07