Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 452313Generated: October 29, 2026

2-Chloroquinoline → 2-(1H-Indol-5-yl)quinoline

https://huagongshe.com/reaction/452313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloroquinolineHCID 11928—
Reactant1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indoleHCID 16217778—
Product2-(1H-Indol-5-yl)quinolineHCID 58362351—

Reaction Steps

2-(1H-indol-5-yl)quinoline was prepared using general procedure A from 2-chloroquinoline (32 mg, 0.2 mmol) and 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (51 mg, 0.2 mmol). The product was obtained as off-white solid (22 mg, 42%). MS (ESI): 245 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08491869B2
Source datasetuspto-grants-2013_07
ORD IDord-b334fb72d10c47d990f76a3c0e65da3d
Source noteuspto-grants-2013_07