HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Phenylenediamine → HCID 370919, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Phenylenediamine | HCID 7243 | — |
| Reactant | 1,2-Dihydro-2-oxocyclohepta[b]pyrrole-3-carboxaldehyde | HCID 10035068 | — |
| Reactant | Sodium Bisulfite | HCID 23665763 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 370919 | HCID 370919 | 95% |
Reaction Steps
3-Formyl-1-azaazulen-2-one (0.1 mmol) was dissolved in a mixture of 10 mL ethanol and 5 mL water. o-Phenylenediamine (0.15 mmol) and sodium bisulfite (0.2 mmol) were then added and heat to reflux for 1 day. After working up, the residue was then purified by column chromatography to give 8.6 mg of A1, yield 95%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08492374B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-27e5d7a3657c45c3a61bb8a7c20df659 |
| Source note | uspto-grants-2013_07 |